The giant cell tumor of bone were presented as eccentric, expanding bone destruction. Myeloma appeared as irregular or bit like bone destruction, MRI on the formation of "salt and pepper" sign performance. 脊柱巨细胞瘤多呈偏心性膨胀性生长,骨髓瘤呈溶骨性或穿凿样骨质破坏,MRI上形成盐和胡椒征。